Chemical Name: Veratric Acid
Molecular Formula: C9H10O4
CAS Number: 93-07-2
Molecular Weight: 182.17 g/mol
Appearance: White crystalline powder
Melting Point: 178-181°C
Solubility: Soluble in hot water, ethanol, and ether; sparingly soluble in cold water

Table of Contents

Section	Details
1. General Information	Introduction to Veratric Acid, including its structure and common uses
2. Chemical Properties	Overview of key chemical properties such as molecular weight, melting point, and solubility
3. Applications	A detailed discussion of Veratric Acid’s uses in pharmaceuticals, organic synthesis, and other industries
4. Synthesis and Derivatives	Information on the synthesis process and its derivatives in chemical research
5. Safety and Handling	Guidelines for the safe handling and storage of Veratric Acid
6. Safety Data	Hazard classifications, pictograms, and precautionary statements
7. Research and Studies	Summary of recent research focused on Veratric Acid and its applications in various fields

1. General Information

It, also known as 3,4-dimethoxybenzoic Acid, is a naturally occurring phenolic acid in multiple plants. It is structurally characterised by two methoxy groups attached to the benzene ring at the 3rd and 4th positions, making it a dimethoxybenzoic acid derivative. This compound is widely used in the pharmaceutical industry due to its potential antioxidant and anti-inflammatory properties. Veratric acid is also a valuable intermediate in the synthesis of other organic compounds.

2. Chemical Properties

• Molecular Formula: C9H10O4
• Molecular Weight: 182.17 g/mol
• CAS Number: 93-07-2
• Appearance: White crystalline powder
• Melting Point: 178-181°C
• Solubility: Soluble in hot water, ethanol, and ether; sparingly soluble in cold water

Its chemical properties, particularly its solubility and stability, make it suitable for various chemical reactions, especially those requiring a stable phenolic acid.

3. Applications

It has several critical applications:

• The pharmaceutical industry utilises it to synthesise various pharmaceuticals, particularly those with antioxidant properties. Veratric Acid’s potential to scavenge free radicals makes it a candidate for use in formulations to treat inflammatory conditions.
• Organic Synthesis: Veratric acid is employed as an intermediate in organic synthesis to produce more complex chemical compounds. Its structure allows for the introduction of additional functional groups, making it a versatile building block.
• Natural Products Chemistry: Veratric Acid is studied for its role in the biosynthesis of plant-derived compounds. Its presence in natural products is often associated with potential health benefits, leading to its inclusion in nutraceuticals and herbal medicines.
• Polymer Industry: Due to its natural origin and relatively low toxicity, Veratric Acid is sometimes used as a monomer or as a component in the production of biodegradable polymers.

4. Synthesis and Derivatives

Vanillic acid can be synthesised by methylating vanillic acid or demethylating syringic acid. Both methods are available, providing flexibility in obtaining Veratric Acid for various research and industrial purposes. Derivatives of Veratric Acid, such as Veratryl Alcohol, are also crucial in studying ligand-π interactions and various biochemical applications.

5. Safety and Handling

It is generally considered safe when handled properly, though it should still be managed with care in a laboratory or industrial setting. Proper personal protective equipment (PPE), such as gloves and safety glasses, should be used when handling the compound. It should be stored in a cool, dry place, away from incompatible materials such as potent oxidising agents.

6. Safety Data

Hazard Classifications

• Irritant: May irritate the skin and eyes upon contact.
• Environmental Hazard: Although not highly toxic, it should not be released into the environment without proper treatment and disposal.

Pictograms:

• Exclamation Mark (Irritant)

Hazard Statements:

• H315: Causes skin irritation.
• H319: Causes severe eye irritation.

Precautionary Statements:

• P280: Wear protective gloves, protective clothing, and eye protection.
• P264: Wash hands thoroughly after handling.
• P305+P351+P338: If yes, rinse cautiously with water for several minutes. If contact lenses are present and easy to remove, continue rinsing.

7. Research and Studies

Recent research into Veratric Acid has explored its potential as an antioxidant and anti-inflammatory agent. Studies have indicated that Veratric Acid may help reduce oxidative stress, making it a compound of interest in the development of treatments for various chronic conditions. Additionally, its role as an intermediate in the synthesis of other biologically active molecules has been extensively studied, highlighting its importance in medicinal chemistry.

Conclusion

It is a compound of significant interest in industrial and research settings, particularly for its versatility in organic synthesis and potential health benefits. Understanding its properties, applications, and safety considerations is crucial for the effective use of this material in various chemical processes. By adhering to proper safety protocols and utilising veratric acid's unique characteristics, this compound can be effectively integrated into numerous scientific and industrial applications.

Related Blog

• cyclopropane carbonyl chloride (CPCC)

• cyclopropane carboxylic acid

FAQ

What is the use of Veratric acid?

Veratric acid (3,4-dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, and has antioxidant and anti-inflammatory activities.

What is 3 4 di methoxy benzoic acid?

Derivative of Protocatechuic Acid, and is a reagent used in the production of antimicrobial agents, antifeedants, and a variety of other biologically active compounds.

What is Acetoxybenzoic acid?

Acetoxybenzoic acid is the chemical name of aspirin, a commonly used antipyretic medicine that lowers fever.

What is acid used for?

Cids are often used to remove rust and other corrosion from metals in a process known as pickling.